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In double-blind, placebo-controlled trials, daily application of GHK-Cu cream at 3% concentration for 12 weeks produced a 70% increase in skin collagen thickness as measured by ultrasound imaging, a 40% increase in skin elasticity, and visible reduction in fine lines and wrinkles

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"In this case, there was enough conversation, and you had people walking off the podium," said researcher Oliver Catlin, president of the Anti-Doping Sciences Institute

5.2 Oral treatment 5.2.1 Tranexamic acid Oral tranexamic acid has been shown to be effective as an adjuvant therapy for refractory cases of melasma or as a second or third-line of treatment (Kim et al., 2017)

Khavinson VKh, Linkova NS, Kvetnoy IM, Kvetnaia TV, Polyakova VO, Korf HW